Human Protein Phosphatase Pseudogene - Revision history

Mark: /* Functions */

2015-10-08T18:11:21Z

‎Functions

2015-10-08T18:09:25Z

2015-10-08T18:07:53Z

2015-10-08T18:05:06Z

2015-10-08T18:01:10Z

2015-10-08T17:46:20Z

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2015-10-08T17:15:38Z

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 == Functions ==
-Almost all of the pseudogenes are functional unknown, but they may have certain functions. The best example is PTENP1, which is a processed pseudogene of PTEN and regulates PTEN by both sense and antisense RNAs. DUSP5P1 may be also functional, as implicated by that it is highly expressed in Hodgkin's lymphoma cell line L-1236 but not in normal blood cells or Epstein-Barr virus-immortalized B cells.
+Almost all of the pseudogenes are functional unknown, but they may have certain functions. The best example is PTENP1, which is a processed pseudogene of PTEN and regulates PTEN by both sense and antisense RNAs. DUSP5P1 may be also functional, as implicated by that it is highly expressed in Hodgkin's lymphoma cell line L-1236 but not in normal blood cells or Epstein-Barr virus-immortalized B cells. Besides, there are putative disease-related SNPs within or adjacent to the regions of the pseudogenes, as found by genome-wide association studies (GWAS).
 == List of pseudogenes ==

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 == Functions ==
-Almost all of the pseudogenes are functional unknown, but they may have certain functions.
+Almost all of the pseudogenes are functional unknown, but they may have certain functions. The best example is PTENP1, which is a processed pseudogene of PTEN and regulates PTEN by both sense and antisense RNAs. DUSP5P1 may be also functional, as implicated by that it is highly expressed in Hodgkin's lymphoma cell line L-1236 but not in normal blood cells or Epstein-Barr virus-immortalized B cells.
-−
 == List of pseudogenes ==

← Older revision		Revision as of 18:07, 8 October 2015
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		+
		+	== Functions ==
		+	Almost all of the pseudogenes are functional unknown, but they may have certain functions.
		+
		+
		+	== List of pseudogenes ==
	The notes are last updated on 10/08/2015.		The notes are last updated on 10/08/2015.

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 * PGAM1Ps
-* [[Phosphatase_Gene_HsapP759|PGAM1P1]]
+** [[Phosphatase_Gene_HsapP759|PGAM1P1]]
-* [[Phosphatase_Gene_HsapP760|PGAM1P10]]
+** [[Phosphatase_Gene_HsapP760|PGAM1P10]]
-* [[Phosphatase_Gene_HsapP761|PGAM1P11]]
+** [[Phosphatase_Gene_HsapP761|PGAM1P11]]
-* [[Phosphatase_Gene_HsapP762|PGAM1P12]]
+** [[Phosphatase_Gene_HsapP762|PGAM1P12]]
-* [[Phosphatase_Gene_HsapP763|PGAM1P13]]
+** [[Phosphatase_Gene_HsapP763|PGAM1P13]]
-* [[Phosphatase_Gene_HsapP764|PGAM1P14]]
+** [[Phosphatase_Gene_HsapP764|PGAM1P14]]
-* [[Phosphatase_Gene_HsapP765|PGAM1P2]]
+** [[Phosphatase_Gene_HsapP765|PGAM1P2]]
-* [[Phosphatase_Gene_HsapP766|PGAM1P3]]
+** [[Phosphatase_Gene_HsapP766|PGAM1P3]]
-* [[Phosphatase_Gene_HsapP767|PGAM1P4]]
+** [[Phosphatase_Gene_HsapP767|PGAM1P4]]
-* [[Phosphatase_Gene_HsapP768|PGAM1P5]]
+** [[Phosphatase_Gene_HsapP768|PGAM1P5]]
-* [[Phosphatase_Gene_HsapP769|PGAM1P6]]
+** [[Phosphatase_Gene_HsapP769|PGAM1P6]]
-* [[Phosphatase_Gene_HsapP770|PGAM1P7]]
+** [[Phosphatase_Gene_HsapP770|PGAM1P7]]
-* [[Phosphatase_Gene_HsapP771|PGAM1P8]]
+** [[Phosphatase_Gene_HsapP771|PGAM1P8]]
-* [[Phosphatase_Gene_HsapP772|PGAM1P9]]
+** [[Phosphatase_Gene_HsapP772|PGAM1P9]]
 * TPTE2Ps

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 * [[Phosphatase_Gene_HsapP754|SSU72P8]]
 * [[Phosphatase_Gene_HsapP755|CTDSPL2P1]]
-* [[Phosphatase_Gene_HsapP756|DullardP1]]
+* [[Phosphatase_Gene_HsapP756|CTDNEP1P1]]
-* [[Phosphatase_Gene_HsapP757|DullardP2]]
+* [[Phosphatase_Gene_HsapP757|CTDNEP1P2]]
 * [[Phosphatase_Gene_HsapP758|CTDSP2P1]]
 * [[Phosphatase_Gene_HsapP759|PGAM1P1]]

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 * [[Phosphatase_Gene_HsapP743|PTPN11P2]]
 * [[Phosphatase_Gene_HsapP744|PTPN11P3]]
-* [[Phosphatase_Gene_HsapP745|ACP1P1-chr5]]
+* [[Phosphatase_Gene_HsapP745|ACP1P1]]
-* [[Phosphatase_Gene_HsapP746|ACP1P3-chr10]]
+* [[Phosphatase_Gene_HsapP746|ACP1P3]]
 * [[Phosphatase_Gene_HsapP747|SSU72P1]]
 * [[Phosphatase_Gene_HsapP748|SSU72P2]]

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 * [[Phosphatase_Gene_HsapP702|CDC14BL]]: originates from pseudogene CDC14C
-* [[Phosphatase_Gene_HsapP703|DUSP5P1]]: highly expressed in Hodgkin's lymphoma cell line L-1236 but not in normal blood cells or Epstein-Barr virus-immortalized B cells <cite>Staege14</cite>.
+* [[Phosphatase_Gene_HsapP703|DUSP5P1]]: highly expressed in Hodgkin's lymphoma cell line L-1236 but not in normal blood cells or Epstein-Barr virus-immortalized B cells
 * [[Phosphatase_Gene_HsapP704|DUSP5P2]]

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 * [[Phosphatase_Gene_HsapP724|MTMR9LP]]
 * [[Phosphatase_Gene_HsapP725|PTENP1]]
-* [[Phosphatase_Gene_HsapP726|TPTEP1]]
+* [[Phosphatase_Gene_HsapP726|TPTEP1]]:  5' part of psiTPTE22 has no sequence similarity to TPTE and contains a 3.8-kb human endogenous retrovirus (HERV) element.
 * [[Phosphatase_Gene_HsapP727|LOC400927]]
 * [[Phosphatase_Gene_HsapP728|TPTE2P1]]

← Older revision		Revision as of 17:11, 8 October 2015
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		+	The notes are last updated on 10/08/2015.
		+
	* [[Phosphatase_Gene_HsapP701\|CDC14C]]: emerged through retroposition in the hominoid ancestor 18-25 million years ago		* [[Phosphatase_Gene_HsapP701\|CDC14C]]: emerged through retroposition in the hominoid ancestor 18-25 million years ago