Phosphatase Family NagD - Revision history

Gerard at 20:15, 21 March 2015

2015-03-21T20:15:56Z

2015-03-21T19:50:27Z

2015-03-09T18:44:30Z

2015-03-09T17:31:28Z

2015-03-09T05:01:59Z

2015-03-09T05:01:12Z

2015-03-09T04:56:28Z

2015-03-09T04:55:08Z

2015-03-09T04:45:00Z

2015-03-09T04:43:28Z

← Older revision		Revision as of 20:15, 21 March 2015
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	* [[Phosphatase_Subfamily_LHPP\|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoa.		* [[Phosphatase_Subfamily_LHPP\|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoa.

−	* [[Phosphatase_Subfamily_CUT\|CUT]] - ~~no strong evidence supports it has~~ protein phosphatase ~~activity~~.	+	* [[Phosphatase_Subfamily_CUT\|CUT]] is a mitochondrial-associated probable non-protein phosphatase.

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 The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies:
-* [[Phosphatase_Subfamily_PGP|PGP]] is a ubiquitous HAD subfamily in eukaryotes. The two members in human have distinct functions: PDXP (aka chronophin) dephosphorylates protein cofilin on serine residue, as well as pyridoxal 5'-phosphate; PGP is a putative tyrosine-specific protein phosphatase. PDXP is mainly expressed in brain; PGP is widely expressed in different tissues.
+* [[Phosphatase_Subfamily_PGP|PGP]] is ubiquitous in eukaryotes. The two members in human have distinct functions: PGP is a putative tyrosine-specific protein phosphatase, and PDXP (chronophin) dephosphorylates cofilin on serine, and also dephosphorylates pyridoxal 5'-phosphate. PDXP is mainly expressed in brain; PGP is widely expressed in different tissues.
-* [[Phosphatase_Subfamily_LHPP|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoan.
+* [[Phosphatase_Subfamily_LHPP|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoa.
 * [[Phosphatase_Subfamily_CUT|CUT]] - no strong evidence supports it has protein phosphatase activity.

@@ Line 3: / Line 3: @@
 The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies:
-* [[Phosphatase_Subfamily_PGP|PGP]]
+* [[Phosphatase_Subfamily_PGP|PGP]] is a ubiquitous HAD subfamily in eukaryotes. The two members in human have distinct functions: PDXP (aka chronophin) dephosphorylates protein cofilin on serine residue, as well as pyridoxal 5'-phosphate; PGP is a putative tyrosine-specific protein phosphatase. PDXP is mainly expressed in brain; PGP is widely expressed in different tissues.
 * [[Phosphatase_Subfamily_LHPP|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoan.
 * [[Phosphatase_Subfamily_CUT|CUT]] - no strong evidence supports it has protein phosphatase activity.

@@ Line 3: / Line 3: @@
 The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies:
 * [[Phosphatase_Subfamily_PGP|PGP]]
 * [[Phosphatase_Subfamily_LHPP|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoan.
 * [[Phosphatase_Subfamily_CUT|CUT]] - no strong evidence supports it has protein phosphatase activity.

@@ Line 1: / Line 1: @@
 [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HAD|Fold HAD]]: [[Phosphatase_Superfamily_HAD|Superfamily HAD]]: [[Phosphatase_Family_NagD|Family NagD]]
-The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies containing protein phosphatases:
+The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies:
 * [[Phosphatase_Subfamily_PGP|PGP]]

← Older revision		Revision as of 05:01, 9 March 2015
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	* [[Phosphatase_Subfamily_LHPP\|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoan.		* [[Phosphatase_Subfamily_LHPP\|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoan.

−	* [[Phosphatase_Subfamily_CUT\|CUT]]	+	* [[Phosphatase_Subfamily_CUT\|CUT]] - no strong evidence supports it has protein phosphatase activity.

← Older revision		Revision as of 04:43, 9 March 2015
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−	[[Phosphatase classification\|Phosphatase Classification]]: [[~~Phosphatase_Group_HAD~~\|Superfamily HAD]]: [[Phosphatase_Family_NagD\|Family NagD]]	+	[[Phosphatase classification\|Phosphatase Classification]]: [[Phosphatase_Fold_HAD\|Fold HAD]]: [[Phosphatase_Superfamily_HAD\|Superfamily HAD]]: [[Phosphatase_Family_NagD\|Family NagD]]

	The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies:		The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies: