Phosphatase Family SSU72 - Revision history

Gerard at 18:20, 12 November 2016

2016-11-12T18:20:55Z

2016-11-12T18:20:15Z

2016-11-12T18:19:27Z

2016-11-12T18:14:51Z

2016-11-12T18:14:00Z

2014-12-06T20:24:57Z

2014-06-16T01:11:50Z

2014-05-27T04:47:40Z

2014-05-01T05:08:03Z

2014-04-30T16:46:34Z

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 __NOTOC__
 [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_CC2|Superfamily CC2]]: [[Phosphatase_Family_SSU72|Family SSU72]]
 ===Evolution===

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 ===Evolution===
-SSU72 is found in most eukaryotes, but is lost in most excavates and some chromalveolates. It is usually present in one copy, but humans also have 7 SSU72 retrogenes of unknown function.
+SSU72 is found in most eukaryotes, but is lost in most excavates and some chromalveolates. It is usually present in one copy, but humans also have 8 SSU72 retrogenes of unknown function.
 ===Domain Architecture===

@@ Line 3: / Line 3: @@
 ===Evolution===
-Ssu72 can be found in all the unikonts (animals, choanoflagellates, fungi, and amoebozoan), plants/algae, Heterokonts, Trichomonas vaginalis (but not Giardia or Trypanasoma or Leishmania). Most SSU72 consist almost entirely of the phosphatase domain.
+SSU72 is found in most eukaryotes, but is lost in most excavates and some chromalveolates. It is usually present in one copy, but humans also have 7 SSU72 retrogenes of unknown function.
 ===Function===

@@ Line 2: / Line 2: @@
 [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_CC2|Superfamily CC2]]: [[Phosphatase_Family_SSU72|Family SSU72]]
-====Evolution====
+===Evolution===
 Ssu72 can be found in all the unikonts (animals, choanoflagellates, fungi, and amoebozoan), plants/algae, Heterokonts, Trichomonas vaginalis (but not Giardia or Trypanasoma or Leishmania). Most SSU72 consist almost entirely of the phosphatase domain.
-====Function====
+===Function===
 The phosphatase activity of Ssu72 is important for Pol II transcription and termination and for gene looping. It catalyzes CTD Serine-5 dephosphorylation in association with the Pta1 component of the CPF complex. In yeast, Ssu72 is required for pre-mRNA 3’-end cleavage, but so far no evidence exists implicating mammalian Ssu72 in that processing <cite>Krish04</cite> <cite>Xiang10</cite>.
-==== Reference ====
+===Reference ===
 <biblio>
 #Krish04 pmid=15125841
 #Xiang10 pmid=20861839
 </biblio>

@@ Line 1: / Line 1: @@
 __NOTOC__
 [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_CC2|Superfamily CC2]]: [[Phosphatase_Family_SSU72|Family SSU72]]
 Ssu72 can be found in all the unikonts (animals, choanoflagellates, fungi, and amoebozoan), plants/algae, Heterokonts, Trichomonas vaginalis (but not Giardia or Trypanasoma or Leishmania). Most SSU72 consist almost entirely of the phosphatase domain.
 The phosphatase activity of Ssu72 is important for Pol II transcription and termination and for gene looping. It catalyzes CTD Serine-5 dephosphorylation in association with the Pta1 component of the CPF complex. In yeast, Ssu72 is required for pre-mRNA 3’-end cleavage, but so far no evidence exists implicating mammalian Ssu72 in that processing <cite>Krish04</cite> <cite>Xiang10</cite>.
-== Reference ==
+==== Reference ====
 <biblio>
 #Krish04 pmid=15125841
 #Xiang10 pmid=20861839
 </biblio>

← Older revision		Revision as of 05:08, 1 May 2014
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	== Evolution ==		== Evolution ==
	Ssu72 can be found in all the unikonts (animals, choanoflagellates, fungi, and amoebozoan), plants/algae, Heterokonts, Trichomonas vaginalis (but not Giardia or Trypanasoma or Leishmania).		Ssu72 can be found in all the unikonts (animals, choanoflagellates, fungi, and amoebozoan), plants/algae, Heterokonts, Trichomonas vaginalis (but not Giardia or Trypanasoma or Leishmania).
		+
		+	==Domain Structure==
		+	Most SSU72 consist almost entirely of the phosphatase domain.