Phosphatase Subfamily PP2D1 - Revision history

Gerard at 21:37, 4 March 2017

2017-03-04T21:37:37Z

Gerard at 18:24, 6 March 2016

2016-03-06T18:24:24Z

Gerard at 18:22, 6 March 2016

2016-03-06T18:22:23Z

Gerard: /* Function */

2016-03-06T18:12:15Z

‎Function

Gerard: /* Evolution */

2016-03-06T18:08:33Z

‎Evolution

Gerard: /* Function */

2016-03-06T18:07:14Z

‎Function

Mark at 22:32, 7 June 2015

2015-06-07T22:32:33Z

Mark: Created page with "Phosphatase Classification: Fold PPM (PP2C): Superfamily PPM (PP2C): Phosphatase_Fami..."

2015-06-07T22:32:20Z

Created page with "Phosphatase Classification: Fold PPM (PP2C): Superfamily PPM (PP2C): Phosphatase_Fami..."

New page

[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_PPM|Fold PPM (PP2C)]]: [[Phosphatase_Superfamily_PPM|Superfamily PPM (PP2C)]]: [[Phosphatase_Family_PPM|Family PPM (PP2C)]]: [[Phosphatase_Subfamily_PP2D1|Subfamily PP2D1]]

=== Evolution ===
The PP2D1 subfamily is found in frog, birds, platypus and mammals. It is also found sparsely from Trichoplax to fish, including Nematostella, Saccoglossus, Ciona, lancelets, and Tetraodon (but not zebrafish).

=== Domain ===
The PP2D1 subfamily has a single structural domain: the phosphatase domain. It has a predicted nuclear localization signal (NLS) using [http://nls-mapper.iab.keio.ac.jp/cgi-bin/NLS_Mapper_form.cgi NLS mapper] and [http://www.moseslab.csb.utoronto.ca/NLStradamus/ NLStradamus].

=== Function ===
Human PP2D1 is predicted to be localized to nuclear.

=== References ===
<biblio>
</biblio>

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 === Evolution  ===
-The PP2D1 subfamily is found in eumetazoans but is frequently lost. It is absent from major model systems including Drosophila, C. elegans and the zebrafish.
+The PP2D1 subfamily is found in eumetazoans but is frequently lost. It is absent from major model systems including Drosophila, C. elegans and zebrafish. It has a single human member, PP2D1 (C3orf48).
 === Domain ===

← Older revision		Revision as of 22:32, 7 June 2015
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		+	__NOTOC__
	[[Phosphatase classification\|Phosphatase Classification]]: [[Phosphatase_Fold_PPM\|Fold PPM (PP2C)]]: [[Phosphatase_Superfamily_PPM\|Superfamily PPM (PP2C)]]: [[Phosphatase_Family_PPM\|Family PPM (PP2C)]]: [[Phosphatase_Subfamily_PP2D1\|Subfamily PP2D1]]		[[Phosphatase classification\|Phosphatase Classification]]: [[Phosphatase_Fold_PPM\|Fold PPM (PP2C)]]: [[Phosphatase_Superfamily_PPM\|Superfamily PPM (PP2C)]]: [[Phosphatase_Family_PPM\|Family PPM (PP2C)]]: [[Phosphatase_Subfamily_PP2D1\|Subfamily PP2D1]]

@@ Line 6: / Line 6: @@
 === Domain ===
-The PP2D1 subfamily has a single structural domain: the phosphatase domain. It has a predicted nuclear localization signal (NLS) using [http://nls-mapper.iab.keio.ac.jp/cgi-bin/NLS_Mapper_form.cgi NLS mapper] and [http://www.moseslab.csb.utoronto.ca/NLStradamus/ NLStradamus].
+The PP2D1 subfamily has a single structural domain: the phosphatase domain. It has a predicted nuclear localization signal (NLS) using [http://nls-mapper.iab.keio.ac.jp/cgi-bin/NLS_Mapper_form.cgi NLS mapper] and [http://www.moseslab.csb.utoronto.ca/NLStradamus/ NLStradamus]. [http://www.proteinatlas.org/search/PP2D1 Protein Atlas] reports it to be found in the nucleoplasm and intermediate filaments, by high-throughput antibody staining.
 === Function ===

@@ Line 9: / Line 9: @@
 === Function ===
-The only publications on any member of the subfamily are showing high-throughput interaction between human PP2D2 and the amyloid protein Abeta <cite></cite>
+The only publications on any member of the subfamily are showing high-throughput interaction between human PP2D2 and the amyloid protein Abeta <cite>Virok</cite>
 === References ===
 <biblio>
 </biblio>