Phosphatase Superfamily AP - Revision history

Mark: /* Evolution */

2015-01-05T15:47:17Z

‎Evolution

Mark at 04:59, 4 January 2015

2015-01-04T04:59:34Z

Mark at 21:00, 30 December 2014

2014-12-30T21:00:35Z

Mark: Mark moved page Phosphatase Superfamily Alkaline Phosphatase to Phosphatase Superfamily AP

2014-12-30T20:57:03Z

Mark moved page Phosphatase Superfamily Alkaline Phosphatase to Phosphatase Superfamily AP

Mark at 20:56, 30 December 2014

2014-12-30T20:56:52Z

Gerard at 19:04, 30 December 2014

2014-12-30T19:04:07Z

Mark: Created page with "Phosphatase Classification: Alkaline phosphatase superfamily ===Alkaline phosphatase superfam..."

2014-06-17T16:31:16Z

Created page with "Phosphatase Classification: Alkaline phosphatase superfamily ===Alkaline phosphatase superfam..."

New page

[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Alkaline_Phosphatase|Alkaline phosphatase superfamily]]

===Alkaline phosphatase superfamily===
Alkaline phosphatases are a superfamily ([http://pfam.xfam.org/family/PF00245 Pfam]) with a wide variety of substrates, possibly including phosphoproteins. There are four human alkaline phosphatases, named by their tissue expression: [http://www.ncbi.nlm.nih.gov/gene/248 ALPI] (alkaline phosphatase, intestinal), [http://www.ncbi.nlm.nih.gov/gene/250 ALPP] (alkaline phosphatase, placental), [http://www.ncbi.nlm.nih.gov/gene/251 ALPPL2] (alkaline phosphatase, placental-like 2), and [http://www.ncbi.nlm.nih.gov/gene/249 ALPL] (alkaline phosphatase, liver/bone/kidneytissue). Early reports found that ALPL and ALPI can dephosphorylate Histone H2A <cite>Swarup, Chan</cite> and that PLAP is a protein tyrosine phosphatase <cite>Telfer</cite>, but their physiological relevance as protein phosphatases is still unclear.

Alkaline phosphatases are found in metazoa, fungi and some protists, but are absent from most plants, and are also found in bacteria. They belong to the alkaline phosphatase-like fold ([http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.d.bah.A.html SCOP]), which contains other enzymes, such as phosphoesterases and sulfatases.

===References===
<biblio>
#Swarup pmid=6167574
#Telfer pmid=8396040
#Chan pmid=3011792
</biblio>

@@ Line 1: / Line 1: @@
 [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_AP|Fold AP]]: [[Phosphatase_Superfamily_AP|Superfamily AP]] (Alkaline phosphatase)
 === Evolution ===
 Alkaline phosphatases are found in metazoa, fungi, some protists, and bacteria, but are absent from most plants. They belong to the alkaline phosphatase-like fold ([http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.d.bah.A.html SCOP]), which contains other enzymes, such as phosphoesterases and sulfatases.
 === Functions ===

@@ Line 1: / Line 1: @@
 [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_AP|Fold AP]]: [[Phosphatase_Superfamily_AP|Superfamily AP]] (Alkaline phosphatase)
-Alkaline phosphatases are a superfamily ([http://pfam.xfam.org/family/PF00245 Pfam]) with a wide variety of substrates, possibly including phosphoproteins. There are four human alkaline phosphatases, named by their tissue expression: [http://www.ncbi.nlm.nih.gov/gene/248 ALPI] (alkaline phosphatase, intestinal), [http://www.ncbi.nlm.nih.gov/gene/250 ALPP] (alkaline phosphatase, placental), [http://www.ncbi.nlm.nih.gov/gene/251 ALPPL2] (alkaline phosphatase, placental-like 2), and [http://www.ncbi.nlm.nih.gov/gene/249 ALPL] (alkaline phosphatase, liver/bone/kidneytissue). Early reports found that ALPL and ALPI can dephosphorylate Histone H2A <cite>Swarup, Chan</cite> and that PLAP is a protein tyrosine phosphatase <cite>Telfer</cite>, but their physiological relevance as protein phosphatases is still unclear.
+=== Evolution ===
-−
 Alkaline phosphatases are found in metazoa, fungi, some protists, and bacteria, but are absent from most plants. They belong to the alkaline phosphatase-like fold ([http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.d.bah.A.html SCOP]), which contains other enzymes, such as phosphoesterases and sulfatases.
 It has a single [[Phosphatase_Family_AP|family AP]] and [[Phosphatase_Subfamily_AP|subfamily AP]].

@@ Line 1: / Line 1: @@
 [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_AP|Fold AP]]: [[Phosphatase_Superfamily_AP|Superfamily AP]] (Alkaline phosphatase)
 Alkaline phosphatases are a superfamily ([http://pfam.xfam.org/family/PF00245 Pfam]) with a wide variety of substrates, possibly including phosphoproteins. There are four human alkaline phosphatases, named by their tissue expression: [http://www.ncbi.nlm.nih.gov/gene/248 ALPI] (alkaline phosphatase, intestinal), [http://www.ncbi.nlm.nih.gov/gene/250 ALPP] (alkaline phosphatase, placental), [http://www.ncbi.nlm.nih.gov/gene/251 ALPPL2] (alkaline phosphatase, placental-like 2), and [http://www.ncbi.nlm.nih.gov/gene/249 ALPL] (alkaline phosphatase, liver/bone/kidneytissue). Early reports found that ALPL and ALPI can dephosphorylate Histone H2A <cite>Swarup, Chan</cite> and that PLAP is a protein tyrosine phosphatase <cite>Telfer</cite>, but their physiological relevance as protein phosphatases is still unclear.
 Alkaline phosphatases are found in metazoa, fungi, some protists, and bacteria, but are absent from most plants. They belong to the alkaline phosphatase-like fold ([http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.d.bah.A.html SCOP]), which contains other enzymes, such as phosphoesterases and sulfatases.
 ===References===

← Older revision		Revision as of 20:56, 30 December 2014
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−	[[Phosphatase classification\|Phosphatase Classification]]: [[~~Phosphatase_Superfamily_Alkaline_Phosphatase~~\|~~Alkaline phosphatase superfamily~~]]	+	[[Phosphatase classification\|Phosphatase Classification]]: [[Phosphatase_Fold_AP\|Fold AP]]: [[Phosphatase_Superfamily_AP\|Superfamily AP]] (Alkaline phosphatase)

	===Alkaline phosphatase superfamily===		===Alkaline phosphatase superfamily===

← Older revision	Revision as of 20:57, 30 December 2014
(No difference)