Difference between revisions of "Phosphatase Family HP2"

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(Subfamilies)
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HP|Fold HP]]: [[Phosphatase_Superfamily_HP|Superfamily HP]] (histidine phosphatase): [[Phosphatase_Family_HP2|Family HP, branch 2]]
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HP|Fold HP]]: [[Phosphatase_Superfamily_HP|Superfamily HP]] (histidine phosphatase): [[Phosphatase_Family_HP2|Family HP, branch 2 (HP2)]]
  
 
Refer to Pfam ID [http://pfam.xfam.org/family/PF00328 PF00328] for general information.
 
Refer to Pfam ID [http://pfam.xfam.org/family/PF00328 PF00328] for general information.
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=== Subfamilies ===
 
=== Subfamilies ===
  
====== [[Phosphatase_Subfamily_ACP2|ACP2]] ======
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* [[Phosphatase_Subfamily_ACP2|ACP2]] is a '''protein phosphatase''' subfamily that usually has multiple copies per genome. Human has three copies with different tissue specificity. It is found in holozoa, ameobozoa, and some protists.
ACP2 is a protein phosphatase subfamily that usually has multiple copies per genome. Human has three copies with different tissue specificity. It is found in holozoa, ameobozoa, and some protists.
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====== [[Phosphatase_Subfamily_ACP6|ACP6]] ======
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* [[Phosphatase_Subfamily_ACP6|ACP6]]
  
====== [[Phosphatase_Subfamily_MINPP1|MINPP1]] ======
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* [[Phosphatase_Subfamily_MINPP1|MINPP1]] is a non-protein phosphatase found in a broad of eukaryotes, including most metazoan and amoebazoan. Known substrates include InsP6 and 2,3-BPG.
MINPP1 is a non-protein phosphatase found in a broad of eukaryotes, including most metazoan and amoebazoan. Known substrates include InsP6 and 2,3-BPG.
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====== [[Phosphatase_Subfamily_PXYLP1|PXYLP1]] (ACPL2) ======
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* [[Phosphatase_Subfamily_PXYLP1|PXYLP1]] (ACPL2) dephosphorylates [http://en.wikipedia.org/wiki/Xylose xylose], a sugar, in the glycosaminoglycan-protein linkage region of proteoglycans <cite>koike14</cite>. It is widely found in bilateria.
PXYLP1 dephosphorylates [http://en.wikipedia.org/wiki/Xylose xylose], a sugar, in the glycosaminoglycan-protein linkage region of proteoglycans <cite>koike14</cite>. It is widely found in bilateria.
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======[[Phosphatase_Subfamily_ PPIP5K| PPIP5K]] ======
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* [[Phosphatase_Subfamily_ PPIP5K| PPIP5K]] has a pseudophosphatase domain which bind to PtdIns(3,4,5)P3. It also has a kinase domain of RimK superfamily, which converts InsP6 and 5-InsP7 to 1-InsP7 and InsP8.
PPIP5K has a pseudophosphatase domain which bind to PtdIns(3,4,5)P3 and a kinase domain of RimK superfamily. The proteins therefore show kinase activity which convert InsP6 and 5-InsP7 to 1-InsP7 and InsP8.
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======[[Phosphatase_Subfamily_cf60|cf60]] ======
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* [[Phosphatase_Subfamily_cf60|Cf60]] is cellular slime mold specific '''pseudophosphatase'''. It encodes a secreted 450-kDa complex of proteins called counting factor (CF), through which Dictyostelium discoideum cells sense and regulate the size of groups and fruiting bodies using.  
Cf60 is cellular slime mold specific.
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===References===
 
===References===

Revision as of 19:42, 30 May 2015

Phosphatase Classification: Fold HP: Superfamily HP (histidine phosphatase): Family HP, branch 2 (HP2)

Refer to Pfam ID PF00328 for general information.

Subfamilies

  • ACP2 is a protein phosphatase subfamily that usually has multiple copies per genome. Human has three copies with different tissue specificity. It is found in holozoa, ameobozoa, and some protists.
  • MINPP1 is a non-protein phosphatase found in a broad of eukaryotes, including most metazoan and amoebazoan. Known substrates include InsP6 and 2,3-BPG.
  • PXYLP1 (ACPL2) dephosphorylates xylose, a sugar, in the glycosaminoglycan-protein linkage region of proteoglycans [1]. It is widely found in bilateria.
  • PPIP5K has a pseudophosphatase domain which bind to PtdIns(3,4,5)P3. It also has a kinase domain of RimK superfamily, which converts InsP6 and 5-InsP7 to 1-InsP7 and InsP8.
  • Cf60 is cellular slime mold specific pseudophosphatase. It encodes a secreted 450-kDa complex of proteins called counting factor (CF), through which Dictyostelium discoideum cells sense and regulate the size of groups and fruiting bodies using.

References

Error fetching PMID 11067847:
Error fetching PMID 9705354:
Error fetching PMID 24425863:
  1. Error fetching PMID 24425863: [koike14]
  2. Error fetching PMID 11067847: [ACPP_1]
  3. Error fetching PMID 9705354: [ACPP_2]
All Medline abstracts: PubMed | HubMed